Enalapril 2 5 mgthe active ingredient enalapril maleate, each tablet contains the following. a few cases of lithium toxicity have been reported in patients receiving concomitant enalapril maleate and lithium and were reversible upon discontinuation of both drugs. maleate (unii: 9o25354epj) (enalaprilat anhydrous - unii:q508q118jm). clinically stable asymptomatic patients with left ventricular dysfunction (ejection fraction ≤35 percent), enalapril maleate decreases the rate of development of overt heart failure and decreases the incidence of hospitalization for heart failure (see clinical pharmacology, heart failure, mortality trials for details and limitations of survival trials). pregnancy is detected, discontinue enalapril maleate as soon as possible. the percentage of patients with severe heart failure (nyha class iv) was 29 percent and 43 percent for patients treated with enalapril maleate and placebo, respectively. potassium sparing agents should generally not be used in patients with heart failure receiving enalapril maleate. oral administration of enalapril maleate, peak serum concentrations of enalapril occur within about one hour. maleate tablets are supplied in the following pack sizes:Blister packs in cardboard outer carton containing 10, 11, 14, 20, 28, 30, 49, (49 x 1 blister),50, 56, 60, 84, 90, 98 100, 250, 500 tablets. using enalapril maleate consideration should be given to the fact that another angiotensin converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that enalapril maleate does not have a similar risk (see warnings).
Enalapril | Side Effects, Dosage, Uses & Moremultiple doses of enalapril maleate in rats do not result in accumulation in any tissues. if the patient's blood pressure is not controlled with enalapril maleate tablets alone, diuretic therapy may be resumed. of the face, extremities, lips, tongue, glottis and/or larynx has been reported in patients treated with angiotensin converting enzyme inhibitors, including enalapril maleate. percent of patients with essential hypertension treated with enalapril maleate alone. in the use of enalapril maleate in children with high blood pressure is limited. considering use of enalapril maleate it should be noted that in controlled clinical trials ace inhibitors have an effect on blood pressure that is less in black patients than in non-blacks. maleate has been evaluated for safety in more than 10,000 patients, including over 1000 patients treated for one year or more. following side effects may happen with this medicine:Stop taking enalapril maleate immediately and go straight away to hospital or seek. avoid use of aliskiren with enalapril maleate in patients with renal impairment (gfr <60 ml/min). pregnant and will advise you to take another medicine instead of enalapril maleate.
it may be advisable to eliminate the diuretic (except in patients with heart failure), reduce the diuretic dose or increase salt intake cautiously before initiating therapy with enalapril maleate in patients at risk for excessive hypotension who are able to tolerate such adjustments (see precautions, drug interactions and adverse reactions). enalapril maleate nor the active diacid was mutagenic in the ames microbial mutagen test with or without metabolic activation. the blood pressure lowering effects of enalapril maleate and thiazides are approximately additive. maleate should not be used in babies or children with kidney problems. administration of enalapril maleate tablets with potassium supplements, potassium salt substitutes, or potassium-sparing diuretics may lead to increases of serum potassium (see precautions). in patients with hypertension the overall percentage of patients treated with enalapril maleate reporting adverse experiences was comparable to placebo. milk of lactating rats contains radioactivity following administration of 14c-enalapril maleate. enalapril maleate is used to treat high blood pressure (hypertension). patients with hypertension or heart failure with no apparent pre-existing renal vascular disease have developed increases in blood urea and serum creatinine, usually minor and transient, especially when enalapril maleate has been given concomitantly with a diuretic. under the headings “do not take enalapril maleate” and “warnings and.
patients with heart problems, enalapril maleate is used in addition to diuretics and where. other ingredients are sodium hydrogen carbonate, pregelatinised starch, maize starch,Lactose monohydrate (see section 2, ‘enalapril maleate contains lactose monohydrate’) and. if oligohydramnios is observed, discontinue enalapril maleate tablets, unless it is considered lifesaving for the mother. is treating you that you are taking enalapril maleate:Any surgery or receive anaesthetics (even at the dentist). the effective half-life of enalaprilat following multiple doses of enalapril maleate is prolonged at this level of renal insufficiency (see dosage and administration). the initial dose of enalapril maleate tablets, the patient should be observed under medical supervision for at least two hours and until blood pressure has stabilized for at least an additional hour (see warnings and precautions, drug interactions). use of enalapril maleate in these age groups is supported by evidence from adequate and well-controlled studies of enalapril maleate in pediatric and adult patients as well as by published literature in pediatric patients (see clinical pharmacology, clinical pharmacology in pediatric patients and dosage and administration). because of the potential for serious adverse reactions in nursing infants from enalapril, a decision should be made whether to discontinue nursing or to discontinue enalapril maleate, taking into account the importance of the drug to the mother.), and especially premature babies, is not recommended whilst taking enalapril maleate. maleate 5 mg tablets are white, arc triangle shaped, with two sides that curve out,Marked with “5” over “g” on one side, and scoreline on the other.