and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: a randomized controlled trial. patients using the topical suspension form of clindamycin:Shake well before applying. small amount of topical foam should be picked up with your fingertips and massaged gently into the affected areas until the foam disappears. objective: to evaluate the therapeutic efficacy of the topical combination of benzoyl peroxide 5% and clindamycin 1% associated with sun exposure for the treatment of progressive macular hypomelanosis.
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& duration: apply topically 2x daily (dosage frequency: 2x daily) for the period of 5 years.]background: topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(s)-chloro-substitution of the 7(r)-hydroxyl group of the parent antibiotic lincomycin.